Homo sapiens Gene: ADAM30
Summary
InnateDB Gene IDBG-101541.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAM30
Gene Name ADAM metallopeptidase domain 30
Synonyms svph4;
Species Homo sapiens
Ensembl Gene ENSG00000134249
Encoded Proteins
ADAM metallopeptidase domain 30
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is testis-specific and contains a polymorphic region, resulting in isoforms with varying numbers of C-terminal repeats. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:119893533-119896495
Strand Reverse strand
Band p12
Transcripts
ENST00000369400 ENSP00000358407
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0007338 single fertilization
GO:0007339 binding of sperm to zona pellucida
GO:0032504 multicellular organism reproduction
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Interaction With The Zona Pellucida pathway
Fertilization pathway
Reproduction pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.283011 Hs.642464
RefSeq NM_021794
HUGO
OMIM
CCDS CCDS907
HPRD 05307
IMGT
EMBL
GenPept
RNA Seq Atlas