Homo sapiens Gene: TUFT1
Summary
InnateDB Gene IDBG-102387.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TUFT1
Gene Name tuftelin 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143367
Encoded Proteins
tuftelin 1
tuftelin 1
tuftelin 1
tuftelin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Tuftelin is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation. [provided by RefSeq, Aug 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:151540305-151583583
Strand Forward strand
Band q21.3
Transcripts
ENST00000368849 ENSP00000357842
ENST00000368848 ENSP00000357841
ENST00000353024 ENSP00000343781
ENST00000392712 ENSP00000376476
ENST00000498606
ENST00000461859
ENST00000490156
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 9 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030345 structural constituent of tooth enamel
Biological Process
GO:0030282 bone mineralization
GO:0042476 odontogenesis
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9NNX1
TrEMBL Q6UWW7
UniProt Splice Variant
Entrez Gene 7286
UniGene Hs.489922
RefSeq NM_001126337 NM_001301317 NM_020127 XM_005245474
HUGO HGNC:12422
OMIM 600087
CCDS CCDS1000 CCDS44223
HPRD 02516
IMGT
EMBL AF254260 AF254850 AF254851 AF254852 AF254854 AF254855 AF254856 AF254857 AF254858 AF254859 AF254860 AK026989 AK075001 AK315414 AL136917 AL365436 AY358610 BC002933 BC008301 CH471121
GenPept AAF78913 AAF78914 AAH02933 AAH08301 AAQ88973 BAB15615 BAC11346 BAG37804 CAB66851 CAI16591 CAI16592 EAW53429 EAW53430 EAW53431 EAW53433
RNA Seq Atlas 7286