Homo sapiens Gene: SYT11
Summary
InnateDB Gene IDBG-103318.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYT11
Gene Name synaptotagmin XI
Synonyms SYT12; sytXI;
Species Homo sapiens
Ensembl Gene ENSG00000132718
Encoded Proteins
synaptotagmin XI
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:155859509-155885199
Strand Forward strand
Band q22
Transcripts
ENST00000368324 ENSP00000357307
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006810 transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0008021 synaptic vesicle
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9BT88
TrEMBL B4DK40
UniProt Splice Variant
Entrez Gene 23208
UniGene Hs.32984 Hs.627498
RefSeq NM_152280 XM_005245014
HUGO HGNC:19239
OMIM 608741
CCDS CCDS1122
HPRD
IMGT
EMBL AK027540 AK074931 AK296378 AL139128 BC004291 BC013690 BC039205 CR749792 D38522
GenPept AAH04291 AAH13690 AAH39205 BAA07527 BAB55186 BAC11300 BAG59052 CAH18653 CAH69948
RNA Seq Atlas 23208