Version 5.4
Homo sapiens Gene: ETV3
Summary
InnateDB Gene IDBG-103660.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ETV3
Gene Name ets variant 3
Synonyms bA110J1.4; METS; PE-1; PE1
Species Homo sapiens
Ensembl Gene ENSG00000117036
Encoded Proteins
IDBP-103662
ets variant 3
IDBP-103664
ets variant 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:157121191-157138474
Strand Reverse strand
Band q23.1
Transcripts
ENST00000368192 ENSP00000357175
ENST00000326786 ENSP00000327316
ENST00000460850
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003674 molecular_function
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0008150 biological_process
GO:0030154 cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0017053 transcriptional repressor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003382
View Gene Order
ENSBTAG00000008649
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt P41162
TrEMBL
UniProt Splice Variant
Entrez Gene 2117
UniGene Hs.709764
RefSeq NM_005240 NM_001145312 XM_006711210
HUGO HGNC:3492
OMIM 164873
CCDS CCDS1164 CCDS44250
HPRD 01282
IMGT
EMBL AF218540 AK304789 AK316274 AL157713 BC022868 CH471121 L16464
GenPept AAA60949 AAH22868 AAK56846 BAG65539 BAH14645 CAC36082 CAH70131 EAW52888
RNA Seq Atlas 2117

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca