Version 5.4
Homo sapiens Gene: CD5L
Summary
InnateDB Gene IDBG-103716.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD5L
Gene Name CD5 molecule-like
Synonyms AIM; API6; PRO229; SP-ALPHA; Spalpha
Species Homo sapiens
Ensembl Gene ENSG00000073754
Encoded Proteins
IDBP-103718
CD5 molecule-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 21730133
CD5L (AIM) is required for obesity-associated recruitment of inflammatory macrophages into adipose tissue. (Demonstrated in mouse)
InnateDB Annotation from Orthologs
Summary
PMID 21730133
[Mus musculus] Cd5l (Aim) is required for obesity-associated recruitment of inflammatory macrophages into adipose tissue.
PMID 24223991
[Mus musculus] Cd5l contributes to the macrophage autophagy mechanisms that lead to Mycobacterium. tuberculosis killing.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:157830914-157898256
Strand Reverse strand
Band q23.1
Transcripts
ENST00000368174 ENSP00000357156
ENST00000484609
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006915 apoptotic process
GO:0006968 cellular defense response
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000015854
View Gene Order
ENSBTAG00000022514
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.134035
RefSeq NM_005894
HUGO
OMIM
CCDS CCDS1171
HPRD 03997
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca