Version 5.4
Homo sapiens Gene: SLAMF7
Summary
InnateDB Gene IDBG-104088.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLAMF7
Gene Name SLAM family member 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000026751
Encoded Proteins
IDBP-104090
SLAM family member 7
IDBP-104092
SLAM family member 7
IDBP-104094
SLAM family member 7
IDBP-389290
SLAM family member 7
IDBP-389291
SLAM family member 7
IDBP-389293
SLAM family member 7
IDBP-389294
SLAM family member 7
IDBP-809000
SLAM family member 7
IDBP-809003
SLAM family member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 18501771
The SLAM and SAP gene families control innate and adaptive immune responses
PMID 19079134
SLAM receptors and SAP influence lymphocyte interactions, development and function
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:160739057-160754821
Strand Forward strand
Band q23.3
Transcripts
ENST00000368043 ENSP00000357022
ENST00000368042 ENSP00000357021
ENST00000359331 ENSP00000352281
ENST00000441662 ENSP00000405605
ENST00000458602 ENSP00000409965
ENST00000444090 ENSP00000416592
ENST00000458104 ENSP00000403294
ENST00000488819
ENST00000495334 ENSP00000473590
ENST00000484221
ENST00000621377 ENSP00000483774
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0030101 natural killer cell activation
GO:0032814 regulation of natural killer cell activation
GO:0042267 natural killer cell mediated cytotoxicity
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038179
View Gene Order
ENSBTAG00000001197
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 57823
UniGene
RefSeq NM_001282588 NM_001282589 NM_001282590 NM_001282591 NM_001282592 NM_001282593 NM_001282594 NM_001282595 NM_001282596 NM_021181
HUGO HGNC:21394
OMIM 606625
CCDS CCDS1209 CCDS60321 CCDS60322 CCDS60323 CCDS60324 CCDS60325 CCDS72956 CCDS72957
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 57823

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca