Version 5.4
Homo sapiens Gene: LY9
Summary
InnateDB Gene IDBG-104095.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LY9
Gene Name lymphocyte antigen 9
Synonyms CD229; hly9; mLY9; SLAMF3
Species Homo sapiens
Ensembl Gene ENSG00000122224
Encoded Proteins
IDBP-104103
lymphocyte antigen 9
IDBP-104105
lymphocyte antigen 9
IDBP-104109
lymphocyte antigen 9
IDBP-104113
lymphocyte antigen 9
IDBP-246136
lymphocyte antigen 9
IDBP-809474
lymphocyte antigen 9
IDBP-809482
lymphocyte antigen 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 18501771
LY9 (SLAMF3) is part of the SLAM and SAP gene families that control innate and adaptive immune responses.
Entrez Gene
Summary LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:160796074-160828261
Strand Forward strand
Band q23.3
Transcripts
ENST00000368039 ENSP00000357018
ENST00000263285 ENSP00000263285
ENST00000368037 ENSP00000357016
ENST00000368035 ENSP00000357014
ENST00000392203 ENSP00000376039
ENST00000474998 ENSP00000476321
ENST00000480837
ENST00000490902 ENSP00000473643
ENST00000471816
ENST00000485624
ENST00000479663
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000004707
View Gene Order
ENSBTAG00000002947
Not yet available
Pathways
NETPATH
NetPath_11
TCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.403857
RefSeq NM_001033667 NM_001261456 NM_001261457 NM_002348
HUGO
OMIM
CCDS CCDS30916 CCDS30917 CCDS65695 CCDS65696
HPRD 02817
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca