Version 5.4
Homo sapiens Gene: RGS16
Summary
InnateDB Gene IDBG-105253.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGS16
Gene Name regulator of G-protein signaling 16
Synonyms A28-RGS14; A28-RGS14P; RGS-R
Species Homo sapiens
Ensembl Gene ENSG00000143333
Encoded Proteins
IDBP-105255
regulator of G-protein signaling 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
The protein encoded by this gene belongs to the \'regulator of G protein signaling\' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:182598623-182604408
Strand Reverse strand
Band q25.3
Transcripts
ENST00000367558 ENSP00000356529
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 15 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
GO:0007601 visual perception
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0038032 termination of G-protein coupled receptor signaling pathway
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026475
View Gene Order
ENSBTAG00000004305
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
INOH website
GPCR signaling pathway
PID NCI
Cross-References
SwissProt O15492
TrEMBL
UniProt Splice Variant
Entrez Gene 6004
UniGene Hs.413297
RefSeq NM_002928
HUGO HGNC:9997
OMIM 602514
CCDS CCDS1348
HPRD
IMGT
EMBL AF009356 AF493937 AK311880 AL353778 BC006243 BT006638 CH471067 U70426 U94829
GenPept AAC16912 AAC39642 AAC52040 AAH06243 AAM12651 AAP35284 BAG34821 CAH72419 EAW91129
RNA Seq Atlas 6004

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca