Homo sapiens Gene: RGS16
Summary
InnateDB Gene IDBG-105253.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGS16
Gene Name regulator of G-protein signaling 16
Synonyms A28-RGS14; A28-RGS14P; RGS-R;
Species Homo sapiens
Ensembl Gene ENSG00000143333
Encoded Proteins
regulator of G-protein signaling 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
The protein encoded by this gene belongs to the \'regulator of G protein signaling\' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:182598623-182604408
Strand Reverse strand
Band q25.3
Transcripts
ENST00000367558 ENSP00000356529
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 15 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
GO:0007601 visual perception
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0038032 termination of G-protein coupled receptor signaling pathway
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
EGFR1 pathway
REACTOME
KEGG
INOH
GPCR signaling pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt O15492
TrEMBL
UniProt Splice Variant
Entrez Gene 6004
UniGene Hs.413297
RefSeq NM_002928
HUGO HGNC:9997
OMIM 602514
CCDS CCDS1348
HPRD
IMGT
EMBL AF009356 AF493937 AK311880 AL353778 BC006243 BT006638 CH471067 U70426 U94829
GenPept AAC16912 AAC39642 AAC52040 AAH06243 AAM12651 AAP35284 BAG34821 CAH72419 EAW91129
RNA Seq Atlas 6004