Version 5.4
Homo sapiens Gene: TROVE2
Summary
InnateDB Gene IDBG-105471.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TROVE2
Gene Name TROVE domain family, member 2
Synonyms RO60; RORNP; SSA2
Species Homo sapiens
Ensembl Gene ENSG00000116747
Encoded Proteins
IDBP-105473
TROVE domain family, member 2
IDBP-105475
TROVE domain family, member 2
IDBP-105477
TROVE domain family, member 2
IDBP-105479
TROVE domain family, member 2
IDBP-105481
TROVE domain family, member 2
IDBP-226963
TROVE domain family, member 2
IDBP-722290
IDBP-389830
TROVE domain family, member 2
IDBP-475469
TROVE domain family, member 2
IDBP-483033
TROVE domain family, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:193059422-193091777
Strand Forward strand
Band q31.2
Transcripts
ENST00000367446 ENSP00000356416
ENST00000367443 ENSP00000356413
ENST00000367445 ENSP00000356415
ENST00000367444 ENSP00000356414
ENST00000367441 ENSP00000356411
ENST00000400968 ENSP00000383752
ENST00000432079 ENSP00000472298
ENST00000415442 ENSP00000401176
ENST00000469214
ENST00000460715
ENST00000506303 ENSP00000425296
ENST00000512587 ENSP00000424612
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
Experimentally validated
Total 33 [view]
Protein-Protein 29 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0030620 U2 snRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0002520 immune system development
GO:0006383 transcription from RNA polymerase III promoter
GO:0007224 smoothened signaling pathway
GO:0009411 response to UV
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000018199
View Gene Order
ENSBTAG00000013812
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa05322
Systemic lupus erythematosus pathway
INOH
PID NCI
Cross-References
SwissProt P10155
TrEMBL A0A024R983 D6RDN1 G5E9R9
UniProt Splice Variant
Entrez Gene 6738
UniGene Hs.288178 Hs.595628 Hs.597894
RefSeq NM_004600 XM_006711497 NM_001042369 NM_001042370 NM_001173524 NM_001173525
HUGO HGNC:11313
OMIM 600063
CCDS CCDS1379 CCDS41449 CCDS41450 CCDS53451
HPRD 15964
IMGT
EMBL AK314594 AL136370 AY205314 AY205315 BC036658 CH471067 J04137 M25077 U44388
GenPept AAA35493 AAA35532 AAB81552 AAB81553 AAH36658 AAO47001 AAO47002 BAG37166 EAW91239 EAW91240 EAW91241 EAW91242 EAW91243 EAW91244 EAW91245 EAW91246 EAW91247
RNA Seq Atlas 6738

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca