Version 5.4
Homo sapiens Gene: ZNF281
Summary
InnateDB Gene IDBG-105649.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF281
Gene Name zinc finger protein 281
Synonyms ZBP-99; ZNP-99
Species Homo sapiens
Ensembl Gene ENSG00000162702
Encoded Proteins
IDBP-105651
zinc finger protein 281
IDBP-105653
zinc finger protein 281
IDBP-105655
zinc finger protein 281
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:200404940-200410056
Strand Reverse strand
Band q32.1
Transcripts
ENST00000294740 ENSP00000294740
ENST00000367353 ENSP00000356322
ENST00000367352 ENSP00000356321
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 20 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001047 core promoter binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0010172 embryonic body morphogenesis
GO:0010629 negative regulation of gene expression
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048863 stem cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041483
View Gene Order
ENSBTAG00000047428
Not yet available
Cross-References
SwissProt Q9Y2X9
TrEMBL B3KMX4
UniProt Splice Variant
Entrez Gene 23528
UniGene Hs.59757 Hs.735801
RefSeq NM_001281293 NM_001281294 NM_012482
HUGO HGNC:13075
OMIM
CCDS CCDS1402 CCDS60384
HPRD
IMGT
EMBL AC104461 AF125158 AJ132591 AJ132592 AK022916 AK022921 BC051905 BC060820
GenPept AAD21084 AAH51905 AAH60820 BAG51134 BAG51136 CAB70967 CAB70968
RNA Seq Atlas 23528

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca