Version 5.4
Homo sapiens Gene: EVX1
Summary
InnateDB Gene IDBG-10642.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EVX1
Gene Name even-skipped homeobox 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000106038
Encoded Proteins
IDBP-10644
even-skipped homeobox 1
IDBP-478024
even-skipped homeobox 1
IDBP-718456
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the even-skipped homeobox family characterized by the presence of a homeodomain closely related to the Drosophila even-skipped (eve) segmentation gene of the pair-rule class. The encoded protein may play an important role as a transcriptional repressor during embryogenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:27242700-27247176
Strand Forward strand
Band p15.2
Transcripts
ENST00000222761 ENSP00000222761
ENST00000496902 ENSP00000419266
ENST00000580535 ENSP00000463759
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0009792 embryo development ending in birth or egg hatching
GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000005503
View Gene Order
ENSBTAG00000020919
Not yet available
Cross-References
SwissProt
TrEMBL J3QQJ1
UniProt Splice Variant
Entrez Gene 2128
UniGene Hs.369879 Hs.734224
RefSeq XM_005249639 NM_001989 XM_005249640
HUGO HGNC:3506
OMIM 142996
CCDS CCDS5413
HPRD 00876
IMGT
EMBL AC004080
GenPept
RNA Seq Atlas 2128

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca