Version 5.4
Homo sapiens Protein: EVX1
Summary
InnateDB Protein IDBP-478024.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EVX1
Protein Name even-skipped homeobox 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000419266
InnateDB Gene IDBG-10642 (EVX1)
Protein Structure
UniProt Annotation
Function May play a role in the specification of neuronal cell types.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0009792 embryo development ending in birth or egg hatching
GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P49640
PhosphoSite PhosphoSite-
TrEMBL B4DQJ0
UniProt Splice Variant
Entrez Gene 2128
UniGene Hs.734224
RefSeq NP_001980
HUGO HGNC:3506
OMIM 142996
CCDS CCDS5413
HPRD 00876
IMGT
EMBL AC004080 AK298822 CH236948 CH471073 U68781 U68782 X60655
GenPept AAB07598 BAG60952 CAA43062 EAL24216 EAW93892

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca