Version 5.4
Homo sapiens Gene: HLX
Summary
InnateDB Gene IDBG-106775.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HLX
Gene Name H2.0-like homeobox
Synonyms HB24; HLX1
Species Homo sapiens
Ensembl Gene ENSG00000136630
Encoded Proteins
IDBP-106777
H2.0-like homeobox
IDBP-390029
H2.0-like homeobox
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:220879400-220885059
Strand Forward strand
Band q41
Transcripts
ENST00000366903 ENSP00000355870
ENST00000427693 ENSP00000408248
ENST00000549319
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001889 liver development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0007519 skeletal muscle tissue development
GO:0008284 positive regulation of cell proliferation
GO:0030154 cell differentiation
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0045629 negative regulation of T-helper 2 cell differentiation
GO:0046622 positive regulation of organ growth
GO:0048484 enteric nervous system development
GO:0048513 organ development
GO:0048557 embryonic digestive tract morphogenesis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039377
View Gene Order
ENSBTAG00000014560
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
il12_2pathway
IL12-mediated signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.74870
RefSeq NM_021958
HUGO
OMIM
CCDS CCDS1527
HPRD 00875
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca