Homo sapiens Gene: JAZF1
Summary
InnateDB Gene IDBG-10703.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol JAZF1
Gene Name JAZF zinc finger 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000153814
Encoded Proteins
JAZF zinc finger 1
JAZF zinc finger 1
JAZF zinc finger 1
JAZF zinc finger 1
JAZF zinc finger 1
JAZF zinc finger 1
JAZF zinc finger 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:27830573-28180743
Strand Reverse strand
Band p15.1
Transcripts
ENST00000283928 ENSP00000283928
ENST00000427814 ENSP00000388302
ENST00000430432 ENSP00000387976
ENST00000447620 ENSP00000415096
ENST00000452993 ENSP00000415984
ENST00000420835 ENSP00000401829
ENST00000454041 ENSP00000399083
ENST00000466516
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003714 transcription corepressor activity
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0017053 transcriptional repressor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q86VZ6
TrEMBL C9JGY8 C9JKQ6 C9JWY1 F8WCD3 F8WD35
UniProt Splice Variant
Entrez Gene 221895
UniGene Hs.368944
RefSeq NM_175061 XM_006715656
HUGO HGNC:28917
OMIM 606246
CCDS CCDS5416
HPRD
IMGT
EMBL AC004007 AC004549 AC004885 AC005017 AK091311 AL834234 AY372319 BC042441 CH236948
GenPept AAH42441 AAQ74874 BAG52333 CAD38912 EAL24212
RNA Seq Atlas 221895