Version 5.4
Homo sapiens Gene: JAZF1
Summary
InnateDB Gene IDBG-10703.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol JAZF1
Gene Name JAZF zinc finger 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000153814
Encoded Proteins
IDBP-10707
JAZF zinc finger 1
IDBP-369634
JAZF zinc finger 1
IDBP-369648
JAZF zinc finger 1
IDBP-369652
JAZF zinc finger 1
IDBP-369655
JAZF zinc finger 1
IDBP-369657
JAZF zinc finger 1
IDBP-369660
JAZF zinc finger 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:27830573-28180743
Strand Reverse strand
Band p15.1
Transcripts
ENST00000283928 ENSP00000283928
ENST00000427814 ENSP00000388302
ENST00000430432 ENSP00000387976
ENST00000447620 ENSP00000415096
ENST00000452993 ENSP00000415984
ENST00000420835 ENSP00000401829
ENST00000454041 ENSP00000399083
ENST00000466516
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003714 transcription corepressor activity
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0017053 transcriptional repressor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000063568
View Gene Order
ENSBTAG00000019024
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.368944
RefSeq NM_175061 XM_006715656
HUGO
OMIM
CCDS CCDS5416
HPRD 09373
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca