Homo sapiens Gene: MED6
Summary
InnateDB Gene IDBG-10785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED6
Gene Name mediator complex subunit 6
Synonyms ARC33; NY-REN-28;
Species Homo sapiens
Ensembl Gene ENSG00000133997
Encoded Proteins
mediator complex subunit 6
mediator complex subunit 6
mediator complex subunit 6
mediator complex subunit 6
mediator complex subunit 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:70581257-70600690
Strand Reverse strand
Band q24.2
Transcripts
ENST00000256379 ENSP00000256379
ENST00000430055 ENSP00000413343
ENST00000440435 ENSP00000394502
ENST00000554963 ENSP00000451684
ENST00000555296
ENST00000553611
ENST00000556044
ENST00000556495
ENST00000554870
ENST00000553523
ENST00000556423
ENST00000615788 ENSP00000481920
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 75 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 75 [view]
Protein-Protein 75 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0010467 gene expression
GO:0019827 stem cell maintenance
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0016020 membrane
GO:0016592 mediator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
Hedgehog pathway
REACTOME
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
PPARA activates gene expression pathway
Generic Transcription Pathway pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Transcriptional regulation of white adipocyte differentiation pathway
Metabolism pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Gene Expression pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.497353
RefSeq NM_001284209 NM_001284210 NM_001284211 NM_005466
HUGO
OMIM
CCDS CCDS61483 CCDS61484 CCDS73649 CCDS9805
HPRD 04284
IMGT
EMBL
GenPept
RNA Seq Atlas