Homo sapiens Gene: PAPD7
Summary
InnateDB Gene IDBG-11696.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAPD7
Gene Name PAP associated domain containing 7
Synonyms LAK-1; LAK1; POLK; POLS; TRF4; TRF4-1; TRF41; TUTASE5;
Species Homo sapiens
Ensembl Gene ENSG00000112941
Encoded Proteins
PAP associated domain containing 7
PAP associated domain containing 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:6714605-6757048
Strand Forward strand
Band p15.31
Transcripts
ENST00000230859 ENSP00000230859
ENST00000515721 ENSP00000427232
ENST00000511764
ENST00000514697
ENST00000505457
ENST00000514410
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004652 polynucleotide adenylyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0043221 SMC family protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006261 DNA-dependent DNA replication
GO:0006302 double-strand break repair
GO:0007062 sister chromatid cohesion
GO:0007076 mitotic chromosome condensation
GO:0042493 response to drug
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
RNA degradation pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q5XG87
TrEMBL B4E0T3 B7ZLL4 D6RJD0
UniProt Splice Variant
Entrez Gene 11044
UniGene Hs.481542
RefSeq NM_001171805 NM_001171806 NM_006999 XM_005248234 XM_006714438
HUGO HGNC:16705
OMIM 605198
CCDS CCDS3871
HPRD 09239
IMGT
EMBL AB005754 AC122710 AF089896 AK289857 AK303516 AY623114 BC084567 BC117137 BC126106 BC143882 CH471102 KC424495
GenPept AAD45198 AAH84567 AAI17138 AAI26107 AAI43883 AAT38110 AGE92663 BAA24434 BAF82546 BAG64545 EAX08101
RNA Seq Atlas 11044