Version 5.4
Homo sapiens Gene: FASTKD3
Summary
InnateDB Gene IDBG-11969.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FASTKD3
Gene Name FAST kinase domains 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124279
Encoded Proteins
IDBP-11971
FAST kinase domains 3
IDBP-475681
FAST kinase domains 3
IDBP-476039
FAST kinase domains 3
IDBP-482168
FAST kinase domains 3
IDBP-478535
FAST kinase domains 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:7859159-7869037
Strand Reverse strand
Band p15.31
Transcripts
ENST00000264669 ENSP00000264669
ENST00000282110
ENST00000513658
ENST00000511261 ENSP00000424568
ENST00000507036 ENSP00000421798
ENST00000513577
ENST00000504695 ENSP00000426008
ENST00000507572 ENSP00000422443
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006468 protein phosphorylation
GO:0045333 cellular respiration
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021532
View Gene Order
ENSBTAG00000009400
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.653162
RefSeq NM_024091 XM_006714498
HUGO
OMIM
CCDS CCDS3873
HPRD 10083
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca