Homo sapiens Gene: FASTKD3
Summary
InnateDB Gene IDBG-11969.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FASTKD3
Gene Name FAST kinase domains 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124279
Encoded Proteins
FAST kinase domains 3
FAST kinase domains 3
FAST kinase domains 3
FAST kinase domains 3
FAST kinase domains 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:7859159-7869037
Strand Reverse strand
Band p15.31
Transcripts
ENST00000264669 ENSP00000264669
ENST00000282110
ENST00000513658
ENST00000511261 ENSP00000424568
ENST00000507036 ENSP00000421798
ENST00000513577
ENST00000504695 ENSP00000426008
ENST00000507572 ENSP00000422443
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006468 protein phosphorylation
GO:0045333 cellular respiration
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q14CZ7
TrEMBL D6RC07 D6RHY4
UniProt Splice Variant
Entrez Gene 79072
UniGene Hs.653162
RefSeq NM_024091 XM_006714498
HUGO HGNC:28758
OMIM
CCDS CCDS3873
HPRD 10083
IMGT
EMBL AC010346 BC001295 BC113563
GenPept AAH01295 AAI13564
RNA Seq Atlas 79072