Version 5.4
Mus musculus Gene: Fastkd3
Summary
InnateDB Gene IDBG-164455.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fastkd3
Gene Name FAST kinase domains 3
Synonyms 2310010B21Rik; AW048587
Species Mus musculus
Ensembl Gene ENSMUSG00000021532
Encoded Proteins
IDBP-164459
FAST kinase domains 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124279:
This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:68582248-68592279
Strand Forward strand
Band B3
Transcripts
ENSMUST00000051784 ENSMUSP00000061737
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0005488 binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006468 protein phosphorylation
GO:0045333 cellular respiration
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124279
View Gene Order
ENSBTAG00000009400
Not yet available
Cross-References
SwissProt Q8BSN9
TrEMBL
UniProt Splice Variant
Entrez Gene 69577
UniGene Mm.402767
RefSeq NM_027123 XM_006517364 XM_006517365
OMIM
CCDS CCDS36719
HPRD
IMGT
MGI ID MGI:1916827
MGI Symbol Fastkd3
EMBL AK031142 AK033189 AK036778 BC042506 BC060688
GenPept AAH42506 AAH60688 BAC27277 BAC28191 BAC29573
RNA Seq Atlas 69577

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca