Homo sapiens Gene: TRMU
Summary
InnateDB Gene IDBG-12047.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRMU
Gene Name tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100416
Encoded Proteins
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:46330875-46357340
Strand Forward strand
Band q13.31
Transcripts
ENST00000381021 ENSP00000370409
ENST00000290846 ENSP00000290846
ENST00000381019 ENSP00000370407
ENST00000441818 ENSP00000393014
ENST00000453630 ENSP00000398488
ENST00000456595 ENSP00000413880
ENST00000457572 ENSP00000407700
ENST00000476901
ENST00000486620
ENST00000465378
ENST00000496831
ENST00000485175
ENST00000493556
ENST00000463785
ENST00000479648
ENST00000491612
ENST00000485559
ENST00000470831
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity
GO:0004810 tRNA adenylyltransferase activity
GO:0005524 ATP binding
GO:0008168 methyltransferase activity
GO:0016740 transferase activity
GO:0016783 sulfurtransferase activity
Biological Process
GO:0006529 asparagine biosynthetic process
GO:0008033 tRNA processing
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Sulfur relay system pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.439524 Hs.602392
RefSeq NM_001282782 NM_001282783 NM_001282784 NM_001282785 NM_018006 XM_005261678
HUGO
OMIM
CCDS CCDS14075 CCDS63510
HPRD 15571
IMGT
EMBL
GenPept
RNA Seq Atlas