InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: IGKC

Summary

InnateDB Gene

IDBG-123549.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IGKC

Gene Name

immunoglobulin kappa constant

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000211592

Encoded Proteins

IDBP-123551

immunoglobulin kappa constant

IDBP-811268

immunoglobulin kappa constant

IDBP-811276

immunoglobulin kappa constant

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

IG_C_gene

Genomic Location

Chromosome 2:88857161-89085723

Strand

Reverse strand

Band

p11.2

Transcripts

ENST00000390237	ENSP00000374777
ENST00000614656	ENSP00000478196
ENST00000614252	ENSP00000483856

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003823	antigen binding
GO:0005515	protein binding

Biological Process

GO:0001895	retina homeostasis
GO:0006955	immune response
GO:0006956	complement activation
GO:0006958	complement activation, classical pathway
GO:0038095	Fc-epsilon receptor signaling pathway
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087	innate immune response
GO:0050776	regulation of immune response

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005886	plasma membrane
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle