Homo sapiens Gene: IGHE
Summary
InnateDB Gene IDBG-124356.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IGHE
Gene Name immunoglobulin heavy constant epsilon
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000211891
Encoded Proteins
immunoglobulin heavy constant epsilon
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type IG_C_gene
Genomic Location Chromosome 14:105599941-105601728
Strand Reverse strand
Band q32.33
Transcripts
ENST00000390541 ENSP00000374983
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 5 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003823 antigen binding
GO:0005515 protein binding
Biological Process
GO:0006955 immune response
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
FCERI mediated NF-kB activation pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Innate Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
Immune System pathway
FCERI mediated Ca+2 mobilization pathway
FCERI mediated MAPK activation pathway
KEGG
INOH
PID NCI
IL4-mediated signaling events
Fc-epsilon receptor I signaling in mast cells
Cross-References
SwissProt P01854
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.649351 Hs.741687
RefSeq
HUGO HGNC:5522
OMIM 147180
CCDS
HPRD
IMGT IGHE
EMBL AL928742 J00222 L00022
GenPept AAB59395 AAB59424
RNA Seq Atlas