Version 5.4
Homo sapiens Protein: IGHE
Summary
InnateDB Protein IDBP-124360.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IGHE
Protein Name immunoglobulin heavy constant epsilon
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000374983
InnateDB Gene IDBG-124356 (IGHE)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 5 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003823 antigen binding
GO:0005515 protein binding
Biological Process
GO:0006955 immune response
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR013162 CD80-like, immunoglobulin C2-set
PFAM PF07654
PF08205
PRINTS
PIRSF
SMART SM00407
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P01854
PhosphoSite PhosphoSite-P01854
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.741687
RefSeq
HUGO HGNC:5522
OMIM 147180
CCDS
HPRD
IMGT IGHE
EMBL AL928742 J00222 L00022
GenPept AAB59395 AAB59424

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca