Homo sapiens Gene: ADAM7
Summary
InnateDB Gene IDBG-12445.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAM7
Gene Name ADAM metallopeptidase domain 7
Synonyms ADAM 7; ADAM-7; EAPI; GP-83; GP83;
Species Homo sapiens
Ensembl Gene ENSG00000069206
Encoded Proteins
ADAM metallopeptidase domain 7
ADAM metallopeptidase domain 7
ADAM metallopeptidase domain 7
ADAM metallopeptidase domain 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:24440930-24526970
Strand Forward strand
Band p21.2
Transcripts
ENST00000175238 ENSP00000175238
ENST00000380789 ENSP00000370166
ENST00000441335 ENSP00000393073
ENST00000520720 ENSP00000430400
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL E5RK87
UniProt Splice Variant
Entrez Gene 8756
UniGene Hs.116147
RefSeq NM_003817 XM_005273670
HUGO HGNC:214
OMIM 607310
CCDS CCDS6045
HPRD 07391
IMGT
EMBL AC024958 AC120193
GenPept
RNA Seq Atlas 8756