Mus musculus Gene: Dlx6
Summary
InnateDB Gene IDBG-128244.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dlx6
Gene Name distal-less homeobox 6
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029754
Encoded Proteins
distal-less homeobox 6
distal-less homeobox 6
distal-less homeobox 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006377:
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. This family is comprised of at least 6 different members that encode proteins with roles in forebrain and craniofacial development. This gene is in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:6863334-6868568
Strand Forward strand
Band A1
Transcripts
ENSMUST00000031768 ENSMUSP00000031768
ENSMUST00000160937 ENSMUSP00000124204
ENSMUST00000172943
ENSMUST00000171311 ENSMUSP00000128585
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0030326 embryonic limb morphogenesis
GO:0030855 epithelial cell differentiation
GO:0042472 inner ear morphogenesis
GO:0048646 anatomical structure formation involved in morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0060021 palate development
GO:0060322 head development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Validated transcriptional targets of deltaNp63 isoforms
Cross-References
SwissProt P70397
TrEMBL
UniProt Splice Variant
Entrez Gene 13396
UniGene Mm.439763
RefSeq NM_010057
OMIM
CCDS CCDS51719
HPRD
IMGT
MGI ID MGI:101927
MGI Symbol Dlx6
EMBL AC122240 AF022078 BC114342 EF535989 U67841
GenPept AAB94583 AAC52844 AAI14343 ABQ10645
RNA Seq Atlas 13396