Version 5.4
Mus musculus Gene: Mib1
Summary
InnateDB Gene IDBG-128545.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mib1
Gene Name mindbomb homolog 1 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000024294
Encoded Proteins
IDBP-128547
mindbomb homolog 1 (Drosophila)
IDBP-540167
mindbomb homolog 1 (Drosophila)
IDBP-539788
mindbomb homolog 1 (Drosophila)
IDBP-621310
mindbomb homolog 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101752:
Gene Information
Type Protein coding
Genomic Location Chromosome 18:10725548-10818704
Strand Forward strand
Band A1
Transcripts
ENSMUST00000052838 ENSMUSP00000054428
ENSMUST00000131073
ENSMUST00000124288 ENSMUSP00000114289
ENSMUST00000150000 ENSMUSP00000122879
ENSMUST00000165555 ENSMUSP00000131712
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0001568 blood vessel development
GO:0001701 in utero embryonic development
GO:0001756 somitogenesis
GO:0001841 neural tube formation
GO:0001947 heart looping
GO:0007219 Notch signaling pathway
GO:0007507 heart development
GO:0016567 protein ubiquitination
GO:0045665 negative regulation of neuron differentiation
GO:0045807 positive regulation of endocytosis
Cellular Component
GO:0005813 centrosome
GO:0005886 plasma membrane
GO:0014069 postsynaptic density
GO:0031410 cytoplasmic vesicle
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101752
View Gene Order
ENSBTAG00000007467
Not yet available
Pathways
NETPATH
REACTOME
REACT_196643
Constitutive Signaling by NOTCH1 HD Domain Mutants pathway
REACT_189085
Disease pathway
REACT_196589
Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway
REACT_199382
Signaling by NOTCH1 pathway
REACT_199384
Activated NOTCH1 Transmits Signal to the Nucleus pathway
REACT_199412
Signaling by NOTCH2 pathway
REACT_199410
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_199411
NOTCH2 Activation and Transmission of Signal to the Nucleus pathway
REACT_199405
Signaling by NOTCH1 in Cancer pathway
REACT_199407
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_199406
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_199409
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_199408
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_188257
Signal Transduction pathway
REACT_231152
Signaling by NOTCH pathway
REACT_196591
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118614
Activated NOTCH1 Transmits Signal to the Nucleus pathway
REACT_160205
NOTCH2 Activation and Transmission of Signal to the Nucleus pathway
REACT_160089
Constitutive Signaling by NOTCH1 HD Domain Mutants pathway
REACT_160243
Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway
REACT_160254
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway
REACT_160082
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_160214
Signaling by NOTCH1 in Cancer pathway
REACT_160099
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_111102
Signal Transduction pathway
REACT_118721
Signaling by NOTCH2 pathway
REACT_160301
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_160248
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_299
Signaling by NOTCH pathway
REACT_118859
Signaling by NOTCH1 pathway
REACT_160133
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
notch_pathway
Notch signaling pathway
Cross-References
SwissProt Q80SY4
TrEMBL Q3TSS1
UniProt Splice Variant
Entrez Gene 225164
UniGene Mm.21500 Mm.403028 Mm.471831
RefSeq NM_144860
OMIM
CCDS CCDS29058
HPRD
IMGT
MGI ID MGI:2443157
MGI Symbol Mib1
EMBL AK053035 AK080847 AK129331 AK161848 AY147848 AY149907 AY245539 AY974091 BC011287 BC069870 BC083072
GenPept AAH11287 AAH69870 AAH83072 AAN18022 AAN75492 AAO91933 AAX84653 BAC35245 BAC38042 BAC98141 BAE36604
RNA Seq Atlas 225164

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca