Mus musculus Gene: Tes
Summary
InnateDB Gene IDBG-128948.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tes
Gene Name testis derived transcript
Synonyms D6Ertd352e; Tes1; Tes2; TESS; testin2;
Species Mus musculus
Ensembl Gene ENSMUSG00000029552
Encoded Proteins
testis derived transcript
testis derived transcript
testis derived transcript
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135269:
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:17065149-17105828
Strand Forward strand
Band A2
Transcripts
ENSMUST00000076654 ENSMUSP00000075950
ENSMUST00000115467 ENSMUSP00000111127
ENSMUST00000121170
ENSMUST00000154266 ENSMUSP00000118791
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0042127 regulation of cell proliferation
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL D6RH72
UniProt Splice Variant
Entrez Gene 21753
UniGene Mm.368484 Mm.449845
RefSeq NM_207176
OMIM
CCDS CCDS39429
HPRD
IMGT
MGI ID MGI:105081
MGI Symbol Tes
EMBL AC159332
GenPept
RNA Seq Atlas 21753