Homo sapiens Gene: TES | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-37196.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | TES | ||||||||||||||||||
Gene Name | testis derived transcript (3 LIM domains) | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000135269 | ||||||||||||||||||
Encoded Proteins |
testis derived transcript (3 LIM domains)
testis derived transcript (3 LIM domains)
testis derived transcript (3 LIM domains)
testis derived transcript (3 LIM domains)
testis derived transcript (3 LIM domains)
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 7:116210493-116258783 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q31.2 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | F8W7T0 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 26136 | ||||||||||||||||||
UniGene | Hs.592286 Hs.607407 Hs.630572 | ||||||||||||||||||
RefSeq | NM_015641 NM_152829 XM_005250258 | ||||||||||||||||||
HUGO | HGNC:14620 | ||||||||||||||||||
OMIM | 606085 | ||||||||||||||||||
CCDS | CCDS5763 CCDS5764 | ||||||||||||||||||
HPRD | 05833 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AC073130 | ||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | 26136 | ||||||||||||||||||