Mus musculus Gene: Klc2
Summary
InnateDB Gene IDBG-130893.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klc2
Gene Name kinesin light chain 2
Synonyms 8030455F02Rik; AW212649; KLC 2; KLC-2;
Species Mus musculus
Ensembl Gene ENSMUSG00000024862
Encoded Proteins
kinesin light chain 2
kinesin light chain 2
kinesin light chain 2
kinesin light chain 2
kinesin light chain 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174996:
Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Kinesin consists of 2 light chains, such as KLC2, and 2 heavy chains (see KIF5B; MIM 602809) in a 1:1 stoichiometric ratio (Rahman et al., 1998 [PubMed 9624122]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:5107746-5118560
Strand Reverse strand
Band A
Transcripts
ENSMUST00000025798 ENSMUSP00000025798
ENSMUST00000113728 ENSMUSP00000109357
ENSMUST00000113727 ENSMUSP00000109356
ENSMUST00000116563 ENSMUSP00000112262
ENSMUST00000142255
ENSMUST00000137403
ENSMUST00000149806
ENSMUST00000135827
ENSMUST00000156717 ENSMUSP00000122458
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005515 protein binding
Biological Process
GO:0008088 axon cargo transport
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005871 kinesin complex
GO:0016020 membrane
GO:0035253 ciliary rootlet
GO:0043005 neuron projection
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
MHC class II antigen presentation pathway
Kinesins pathway
Adaptive Immune System pathway
Immune System pathway
Factors involved in megakaryocyte development and platelet production pathway
Hemostasis pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL D3Z5Y7
UniProt Splice Variant
Entrez Gene 16594
UniGene Mm.271648
RefSeq NM_008451 XM_006531667
OMIM
CCDS CCDS37889
HPRD
IMGT
MGI ID MGI:107953
MGI Symbol Klc2
EMBL AC124502
GenPept
RNA Seq Atlas 16594