Version 5.4
Homo sapiens Gene: TTLL5
Summary
InnateDB Gene IDBG-13099.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TTLL5
Gene Name tubulin tyrosine ligase-like family, member 5
Synonyms CORD19; KIAA0998; STAMP
Species Homo sapiens
Ensembl Gene ENSG00000119685
Encoded Proteins
IDBP-13101
tubulin tyrosine ligase-like family, member 5
IDBP-13103
tubulin tyrosine ligase-like family, member 5
IDBP-601963
tubulin tyrosine ligase-like family, member 5
IDBP-588668
tubulin tyrosine ligase-like family, member 5
IDBP-585860
tubulin tyrosine ligase-like family, member 5
IDBP-604060
tubulin tyrosine ligase-like family, member 5
IDBP-813598
tubulin tyrosine ligase-like family, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the tubulin tyrosine ligase like protein family. This protein interacts with two glucocorticoid receptor coactivators, transcriptional intermediary factor 2 and steroid receptor coactivator 1. This protein may function as a coregulator of glucocorticoid receptor mediated gene induction and repression. This protein may also function as an alpha tubulin polyglutamylase.[provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:75633625-75955078
Strand Forward strand
Band q24.3
Transcripts
ENST00000298832 ENSP00000298832
ENST00000286650 ENSP00000286650
ENST00000556265
ENST00000554132
ENST00000555290
ENST00000556977 ENSP00000451917
ENST00000556685
ENST00000557636 ENSP00000450713
ENST00000556173
ENST00000554185
ENST00000555422
ENST00000554935
ENST00000554148
ENST00000554878
ENST00000556976
ENST00000556893 ENSP00000452524
ENST00000554510 ENSP00000451946
ENST00000555018 ENSP00000478640
ENST00000557219
ENST00000554972
ENST00000554487
ENST00000608522
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016874 ligase activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006464 cellular protein modification process
GO:0007283 spermatogenesis
GO:0007288 sperm axoneme assembly
GO:0009566 fertilization
GO:0018095 protein polyglutamylation
GO:0030317 sperm motility
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005929 cilium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000012609
View Gene Order
ENSBTAG00000025403
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.709609
RefSeq NM_015072
HUGO
OMIM
CCDS CCDS32124
HPRD 08309
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca