Version 5.4
Mus musculus Gene: Cks2
Summary
InnateDB Gene IDBG-132350.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cks2
Gene Name CDC28 protein kinase regulatory subunit 2
Synonyms 1110038L14Rik; CKSHS2
Species Mus musculus
Ensembl Gene ENSMUSG00000062248
Encoded Proteins
IDBP-132352
CDC28 protein kinase regulatory subunit 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123975:
CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:51645232-51650660
Strand Forward strand
Band A5
Transcripts
ENSMUST00000075853 ENSMUSP00000075250
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0007049 cell cycle
GO:0007127 meiosis I
GO:0045859 regulation of protein kinase activity
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000123975
View Gene Order
ENSBTAG00000001938
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05222
Small cell lung cancer pathway
mmu05200
Pathways in cancer pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa05222
Small cell lung cancer pathway
hsa05200
Pathways in cancer pathway
INOH
PID NCI
Cross-References
SwissProt P56390
TrEMBL Q545R9
UniProt Splice Variant
Entrez Gene 66197
UniGene Mm.443327
RefSeq NM_025415 XM_006521618 XM_006543248 XM_006543476
OMIM
CCDS CCDS36664
HPRD
IMGT
MGI ID MGI:1913447
MGI Symbol Cks2
EMBL AA041913 AA289122 AK002451 AK004163 AK166688 BC022647 BC094919 CH466536
GenPept AAH22647 AAH94919 BAB22110 BAB23199 BAE38947 EDL14275
RNA Seq Atlas 102638700 102641603 102643116 66197

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca