Version 5.4
Mus musculus Gene: Dap
Summary
InnateDB Gene IDBG-132573.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dap
Gene Name death-associated protein
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039168
Encoded Proteins
IDBP-132575
death-associated protein
IDBP-789623
death-associated protein
IDBP-789624
death-associated protein
IDBP-789625
death-associated protein
IDBP-789626
death-associated protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112977:
This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. [provided by RefSeq, Jul 2008]
This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:31224314-31274341
Strand Forward strand
Band B2
Transcripts
ENSMUST00000044524 ENSMUSP00000047186
ENSMUST00000186109 ENSMUSP00000141108
ENSMUST00000186547 ENSMUSP00000140481
ENSMUST00000186425 ENSMUSP00000140007
ENSMUST00000185618 ENSMUSP00000140568
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0070513 death domain binding
Biological Process
GO:0006914 autophagy
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010507 negative regulation of autophagy
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0034198 cellular response to amino acid starvation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112977
View Gene Order
ENSBTAG00000006346
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 223453
UniGene
RefSeq NM_146057
OMIM
CCDS CCDS27406
HPRD
IMGT
MGI ID MGI:1918190
MGI Symbol Dap
EMBL
GenPept
RNA Seq Atlas 223453

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca