Version 5.4
Mus musculus Gene: Casp8ap2
Summary
InnateDB Gene IDBG-133238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Casp8ap2
Gene Name caspase 8 associated protein 2
Synonyms AA387232; D4Ertd659e; FLASH; mKIAA1315
Species Mus musculus
Ensembl Gene ENSMUSG00000028282
Encoded Proteins
IDBP-133240
caspase 8 associated protein 2
IDBP-265085
caspase 8 associated protein 2
IDBP-718914
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:32615451-32653265
Strand Forward strand
Band A5
Transcripts
ENSMUST00000029950 ENSMUSP00000029950
ENSMUST00000108178 ENSMUSP00000103813
ENSMUST00000124278
ENSMUST00000127619
ENSMUST00000178925 ENSMUSP00000136016
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0002020 protease binding
GO:0003677 DNA binding
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0032184 SUMO polymer binding
GO:0042802 identical protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007049 cell cycle
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0036337 Fas signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016605 PML body
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.22279 Mm.407072
RefSeq NM_001122978 NM_011997 XM_006537949 XM_006537950
OMIM
CCDS CCDS18016
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca