Version 5.4
Homo sapiens Gene: ARID3A
Summary
InnateDB Gene IDBG-13387.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARID3A
Gene Name AT rich interactive domain 3A (BRIGHT-like)
Synonyms BRIGHT; DRIL1; DRIL3; E2FBP1
Species Homo sapiens
Ensembl Gene ENSG00000116017
Encoded Proteins
IDBP-13391
AT rich interactive domain 3A (BRIGHT-like)
IDBP-764235
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:925781-975934
Strand Forward strand
Band p13.3
Transcripts
ENST00000263620 ENSP00000263620
ENST00000585895
ENST00000587532 ENSP00000464969
ENST00000585733
ENST00000590749
ENST00000592216
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0045121 membrane raft
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019564
View Gene Order
ENSBTAG00000008607
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
Cross-References
SwissProt
TrEMBL K7EJ04
UniProt Splice Variant
Entrez Gene 1820
UniGene Hs.501296 Hs.638847
RefSeq NM_005224 XM_005259512 XM_005259513 XM_005259514 XM_005259515
HUGO HGNC:3031
OMIM 603265
CCDS CCDS12050
HPRD 10343
IMGT
EMBL AC005379 AC005391
GenPept
RNA Seq Atlas 1820

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca