InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Arid3a

Summary

InnateDB Gene

IDBG-171662.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Arid3a

Gene Name

AT rich interactive domain 3A (BRIGHT-like)

Synonyms

Bright; Dri1; Dril1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000019564

Encoded Proteins

IDBP-171664

AT rich interactive domain 3A (BRIGHT-like)

IDBP-271007

AT rich interactive domain 3A (BRIGHT-like)

IDBP-271009

AT rich interactive domain 3A (BRIGHT-like)

IDBP-539309

AT rich interactive domain 3A (BRIGHT-like)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116017:
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:79927043-79955018

Strand

Forward strand

Band

Transcripts

ENSMUST00000019708	ENSMUSP00000019708
ENSMUST00000105377	ENSMUSP00000101016
ENSMUST00000105376	ENSMUSP00000101015
ENSMUST00000131118	ENSMUSP00000114261
ENSMUST00000135005

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	3 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0045121	membrane raft

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000116017

View Gene Order

ENSBTAG00000008607

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

INOH

PID NCI

p53downstreampathway

Direct p53 effectors

Cross-References

SwissProt

Q62431

TrEMBL

D3YVQ2

UniProt Splice Variant

Entrez Gene

13496

UniGene

Mm.301282 Mm.471456

RefSeq

NM_001288625 NM_001288626 NM_007880 XM_006513201 XM_006513202

OMIM

CCDS

CCDS23999

HPRD

IMGT

MGI ID

MGI:1328360

MGI Symbol

Arid3a

EMBL

AC151846 AK141283 AK154956 BC050925 U60335

GenPept

AAB03416 AAH50925 BAE24635 BAE32951

RNA Seq Atlas

13496