Version 5.4
Mus musculus Gene: Pcid2
Summary
InnateDB Gene IDBG-134445.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcid2
Gene Name PCI domain containing 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038542
Encoded Proteins
IDBP-626038
PCI domain containing 2
IDBP-626043
PCI domain containing 2
IDBP-626051
PCI domain containing 2
IDBP-626053
PCI domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126226:
PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2 (MAD2L1; MIM 601467) (Nakaya et al., 2010 [PubMed 20870947]).[supplied by OMIM, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:13077189-13105459
Strand Reverse strand
Band A1.1
Transcripts
ENSMUST00000168164 ENSMUSP00000128207
ENSMUST00000164416 ENSMUSP00000133204
ENSMUST00000165097
ENSMUST00000166881
ENSMUST00000167198 ENSMUSP00000130059
ENSMUST00000172443 ENSMUSP00000127622
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0043488 regulation of mRNA stability
GO:0045579 positive regulation of B cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048536 spleen development
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint
GO:2000117 negative regulation of cysteine-type endopeptidase activity
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000126226
View Gene Order
ENSBTAG00000021725
Not yet available
Cross-References
SwissProt Q8BFV2
TrEMBL
UniProt Splice Variant
Entrez Gene 234069
UniGene Mm.103427
RefSeq NM_178708
OMIM
CCDS CCDS52484
HPRD
IMGT
MGI ID MGI:2443003
MGI Symbol Pcid2
EMBL AK042945 AK045796 AK048722 AK163697 BC118533
GenPept AAI18534 BAC31414 BAC32494 BAC33434 BAE37463
RNA Seq Atlas 234069

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca