Version 5.4
Homo sapiens Gene: PCID2
Summary
InnateDB Gene IDBG-52450.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCID2
Gene Name PCI domain containing 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000126226
Encoded Proteins
IDBP-52452
PCI domain containing 2
IDBP-52454
PCI domain containing 2
IDBP-52456
PCI domain containing 2
IDBP-52458
PCI domain containing 2
IDBP-52464
PCI domain containing 2
IDBP-52466
PCI domain containing 2
IDBP-807661
PCI domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2 (MAD2L1; MIM 601467) (Nakaya et al., 2010 [PubMed 20870947]).[supplied by OMIM, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:113177539-113208715
Strand Reverse strand
Band q34
Transcripts
ENST00000337344 ENSP00000337405
ENST00000375479 ENSP00000364628
ENST00000375477 ENSP00000364626
ENST00000246505 ENSP00000246505
ENST00000375459 ENSP00000364608
ENST00000375457 ENSP00000364606
ENST00000493650
ENST00000463102
ENST00000462653
ENST00000473462
ENST00000475433
ENST00000484641
ENST00000480971
ENST00000491548
ENST00000462853
ENST00000622406 ENSP00000479494
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0043488 regulation of mRNA stability
GO:0045579 positive regulation of B cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048536 spleen development
GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint
GO:2000117 negative regulation of cysteine-type endopeptidase activity
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038542
View Gene Order
ENSBTAG00000021725
Not yet available
Cross-References
SwissProt
TrEMBL A0A024RDZ9 A0A024RE04
UniProt Splice Variant
Entrez Gene 55795
UniGene
RefSeq NM_001258212 NM_001127202 NM_001127203 NM_001258213 NM_018386 XM_005268324
HUGO HGNC:25653
OMIM 613713
CCDS CCDS58302 CCDS58301 CCDS9532
HPRD
IMGT
EMBL CH471085
GenPept EAX09189 EAX09192 EAX09193 EAX09194 EAX09195 EAX09196 EAX09197 EAX09198 EAX09199
RNA Seq Atlas 55795

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca