Mus musculus Gene: Rdh10
Summary
InnateDB Gene IDBG-135100.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rdh10
Gene Name retinol dehydrogenase 10 (all-trans)
Synonyms 3110069K09Rik; 4921506A21Rik; AI875664; AW549993; D1Ertd762e; m366Asp;
Species Mus musculus
Ensembl Gene ENSMUSG00000025921
Encoded Proteins
retinol dehydrogenase 10 (all-trans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121039:
This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:16105774-16133734
Strand Forward strand
Band A3
Transcripts
ENSMUST00000027053 ENSMUSP00000027053
ENSMUST00000152626
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004745 retinol dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0052650 NADP-retinol dehydrogenase activity
Biological Process
GO:0001656 metanephros development
GO:0001701 in utero embryonic development
GO:0002138 retinoic acid biosynthetic process
GO:0007601 visual perception
GO:0008152 metabolic process
GO:0008406 gonad development
GO:0009887 organ morphogenesis
GO:0014032 neural crest cell development
GO:0031076 embryonic camera-type eye development
GO:0035115 embryonic forelimb morphogenesis
GO:0042572 retinol metabolic process
GO:0042574 retinal metabolic process
GO:0043583 ear development
GO:0043584 nose development
GO:0048568 embryonic organ development
GO:0048703 embryonic viscerocranium morphogenesis
GO:0055114 oxidation-reduction process
GO:0060431 primary lung bud formation
GO:0060449 bud elongation involved in lung branching
Cellular Component
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0044297 cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Disease pathway
The canonical retinoid cycle in rods (twilight vision) pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
KEGG
Retinol metabolism pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
The canonical retinoid cycle in rods (twilight vision) pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
Disease pathway
The canonical retinoid cycle in rods (twilight vision) pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Disease pathway
KEGG
Retinol metabolism pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8VCH7
TrEMBL
UniProt Splice Variant
Entrez Gene 98711
UniGene Mm.274376 Mm.473291 Mm.473455 Mm.490911
RefSeq NM_133832
OMIM
CCDS CCDS14830
HPRD
IMGT
MGI ID MGI:1924238
MGI Symbol Rdh10
EMBL AF456767 BC019796
GenPept AAH19796 AAN64749
RNA Seq Atlas 98711