InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Dgkb

Summary

InnateDB Gene

IDBG-135780.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dgkb

Gene Name

diacylglycerol kinase, beta

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000036095

Encoded Proteins

IDBP-135784

diacylglycerol kinase, beta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136267:
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:37880705-38633410

Strand

Forward strand

Band

Transcripts

ENSMUST00000040500

ENSMUSP00000037900

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003951	NAD+ kinase activity
GO:0004143	diacylglycerol kinase activity
GO:0005509	calcium ion binding
GO:0005524	ATP binding

Biological Process

GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016310	phosphorylation
GO:0035556	intracellular signal transduction