Version 5.4
Mus musculus Protein: Dgkb
Summary
InnateDB Protein IDBP-135784.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dgkb
Protein Name diacylglycerol kinase, beta
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000037900
InnateDB Gene IDBG-135780 (Dgkb)
Protein Structure
UniProt Annotation
Function Exhibits high phosphorylation activity for long-chain diacylglycerols. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003951 NAD+ kinase activity
GO:0004143 diacylglycerol kinase activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
Biological Process
GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016310 phosphorylation
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2442474
InterPro IPR000756 Diacylglycerol kinase, accessory domain
IPR001206 Diacylglycerol kinase, catalytic domain
IPR002048 EF-hand domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding
PFAM PF00609
PF00781
PF00036
PF13202
PF13405
PF00130
PRINTS
PIRSF
SMART SM00045
SM00046
SM00054
SM00109
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NS52
PhosphoSite PhosphoSite-Q6NS52
TrEMBL Q8BXP8
UniProt Splice Variant
Entrez Gene 217480
UniGene Mm.126525
RefSeq NP_848796
MGI ID
MGI Symbol Dgkb
OMIM
CCDS CCDS25889
HPRD
IMGT
EMBL AK044516 AK047785 AK122355 AK139408 BC070461
GenPept AAH70461 BAC31960 BAC33156 BAC65637 BAE23997

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca