Mus musculus Gene: Pfkfb3
Summary
InnateDB Gene IDBG-136298.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pfkfb3
Gene Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000026773
Encoded Proteins
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170525:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:11471430-11502101
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000028114 ENSMUSP00000028114
ENSMUST00000049849 ENSMUSP00000050926
ENSMUST00000100411 ENSMUSP00000097979
ENSMUST00000114846 ENSMUSP00000110495
ENSMUST00000114845 ENSMUSP00000110494
ENSMUST00000114844 ENSMUSP00000110493
ENSMUST00000150086
ENSMUST00000155167
ENSMUST00000140580
ENSMUST00000144921
ENSMUST00000145970
ENSMUST00000170196 ENSMUSP00000126305
ENSMUST00000171188 ENSMUSP00000129122
ENSMUST00000179584 ENSMUSP00000137130
ENSMUST00000183869 ENSMUSP00000138893
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003873 6-phosphofructo-2-kinase activity
GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524 ATP binding
Biological Process
GO:0006000 fructose metabolic process
GO:0006003 fructose 2,6-bisphosphate metabolic process
GO:0007420 brain development
GO:0016311 dephosphorylation
GO:0046835 carbohydrate phosphorylation
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Fructose and mannose metabolism pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Glycolysis pathway
Metabolism pathway
Disease pathway
Glucose metabolism pathway
Glycogen storage diseases pathway
KEGG
Fructose and mannose metabolism pathway
INOH
Fructose Mannose metabolism pathway
PID BIOCARTA
PID NCI
HIF-1-alpha transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.403577
RefSeq NM_001177752 NM_001177753 NM_001177754 NM_001177755 NM_001177756 NM_001177757 NM_001177758 NM_133232 XM_006497370
OMIM
CCDS CCDS15683 CCDS50498 CCDS50499 CCDS50500 CCDS50501
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas