Version 5.4
Mus musculus Gene: Ubap1
Summary
InnateDB Gene IDBG-137683.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ubap1
Gene Name ubiquitin-associated protein 1
Synonyms 2700092A01Rik; NAG20; Ubap; UBAP-1
Species Mus musculus
Ensembl Gene ENSMUSG00000028437
Encoded Proteins
IDBP-137685
ubiquitin-associated protein 1
IDBP-265342
ubiquitin-associated protein 1
IDBP-535095
ubiquitin-associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165006:
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:41348996-41390525
Strand Forward strand
Band A5
Transcripts
ENSMUST00000072866 ENSMUSP00000072643
ENSMUST00000108060 ENSMUSP00000103695
ENSMUST00000136705
ENSMUST00000154529
ENSMUST00000132235 ENSMUSP00000123491
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043130 ubiquitin binding
Biological Process
GO:0015031 protein transport
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Cellular Component
GO:0000813 ESCRT I complex
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165006
View Gene Order
ENSBTAG00000000320
Not yet available
Cross-References
SwissProt Q8BH48
TrEMBL
UniProt Splice Variant
Entrez Gene 67123
UniGene Mm.289795 Mm.466320
RefSeq NM_001290454 NM_023305 XM_006538196 XM_006538197 XM_006538198 XM_006538199
OMIM
CCDS CCDS51140 CCDS71361
HPRD
IMGT
MGI ID MGI:2149543
MGI Symbol Ubap1
EMBL AF275549 AK009596 AK028477 AK028670 AK030370 AK033121 AK051346 AK076078 BC065996
GenPept AAG09810 AAH65996 BAB26382 BAC25970 BAC26057 BAC26927 BAC28160 BAC34609 BAC36165
RNA Seq Atlas 67123

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca