Version 5.4
Homo sapiens Gene: UBAP1
Summary
InnateDB Gene IDBG-59194.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBAP1
Gene Name ubiquitin associated protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165006
Encoded Proteins
IDBP-59196
ubiquitin associated protein 1
IDBP-59198
ubiquitin associated protein 1
IDBP-59200
ubiquitin associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:34179013-34252523
Strand Forward strand
Band p13.3
Transcripts
ENST00000297661 ENSP00000297661
ENST00000379186 ENSP00000368484
ENST00000359544 ENSP00000352541
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043130 ubiquitin binding
Biological Process
GO:0015031 protein transport
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Cellular Component
GO:0000813 ESCRT I complex
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028437
View Gene Order
ENSBTAG00000000320
Not yet available
Cross-References
SwissProt Q9NZ09
TrEMBL
UniProt Splice Variant
Entrez Gene 51271
UniGene Hs.268963 Hs.739972
RefSeq NM_001171201 NM_001171202 NM_001171203 NM_001171204 NM_016525 XM_006716779
HUGO HGNC:12461
OMIM 609787
CCDS CCDS6550
HPRD 15597
IMGT
EMBL AF222043 AK074724 AK074745 AK074812 AK074969 AK074995 AK223235 AK295482 AK303711 AL136733 AL353662 BC020950 BC098141 BC098316 BC099726 BC100668 CH471071 CR533551
GenPept AAF37827 AAH20950 AAH98141 AAH98316 AAH99726 AAI00669 BAC11162 BAC11176 BAC11224 BAC11323 BAC11342 BAD96955 BAH12084 BAH14025 CAB66667 CAG38582 CAI15914 CAI15915 EAW58467 EAW58468 EAW58469 EAW58470
RNA Seq Atlas 51271

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca