Version 5.4
Mus musculus Gene: Sfi1
Summary
InnateDB Gene IDBG-138079.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sfi1
Gene Name Sfi1 homolog, spindle assembly associated (yeast)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000023764
Encoded Proteins
IDBP-138085
Sfi1 homolog, spindle assembly associated (yeast)
IDBP-138089
Sfi1 homolog, spindle assembly associated (yeast)
IDBP-138091
Sfi1 homolog, spindle assembly associated (yeast)
IDBP-401367
Sfi1 homolog, spindle assembly associated (yeast)
IDBP-534261
Sfi1 homolog, spindle assembly associated (yeast)
IDBP-534534
Sfi1 homolog, spindle assembly associated (yeast)
IDBP-539522
Sfi1 homolog, spindle assembly associated (yeast)
IDBP-533517
Sfi1 homolog, spindle assembly associated (yeast)
IDBP-531579
Sfi1 homolog, spindle assembly associated (yeast)
IDBP-533512
Sfi1 homolog, spindle assembly associated (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198089:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:3131850-3193463
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000101655 ENSMUSP00000099178
ENSMUST00000081318 ENSMUSP00000080066
ENSMUST00000066391 ENSMUSP00000067261
ENSMUST00000118627 ENSMUSP00000113559
ENSMUST00000153425 ENSMUSP00000121719
ENSMUST00000144447
ENSMUST00000140846 ENSMUSP00000119905
ENSMUST00000144778
ENSMUST00000126746 ENSMUSP00000122002
ENSMUST00000132893 ENSMUSP00000118419
ENSMUST00000144359
ENSMUST00000137633
ENSMUST00000138126
ENSMUST00000133882
ENSMUST00000146888
ENSMUST00000141422
ENSMUST00000156655
ENSMUST00000143442
ENSMUST00000142315 ENSMUSP00000118364
ENSMUST00000155763 ENSMUSP00000116369
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019902 phosphatase binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005814 centriole
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198089
View Gene Order
ENSBTAG00000008996
Not yet available
Pathways
NETPATH
REACTOME
REACT_245720
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_240530
G2/M Transition pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_243078
Loss of Nlp from mitotic centrosomes pathway
REACT_188804
Cell Cycle pathway
REACT_246508
Mitotic G2-G2/M phases pathway
REACT_244487
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_196635
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_253753
Centrosome maturation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_15364
Loss of Nlp from mitotic centrosomes pathway
REACT_15451
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_115566
Cell Cycle pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q5NC01
UniProt Splice Variant
Entrez Gene 78887
UniGene Mm.404558 Mm.485866
RefSeq NM_030207 XM_006514894 XM_006514895 XM_006514896 XM_006514897 XM_006514898
OMIM
CCDS CCDS36094
HPRD
IMGT
MGI ID MGI:1926137
MGI Symbol Sfi1
EMBL AL671968 BX572640
GenPept
RNA Seq Atlas 78887

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca