Homo sapiens Gene: SFI1
Summary
InnateDB Gene IDBG-4730.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SFI1
Gene Name Sfi1 homolog, spindle assembly associated (yeast)
Synonyms hSfi1p; PISD; PPP1R139;
Species Homo sapiens
Ensembl Gene ENSG00000198089
Encoded Proteins
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Sfi1 homolog, spindle assembly associated (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:31488688-31618586
Strand Forward strand
Band q12.2
Transcripts
ENST00000357852
ENST00000382162
ENST00000400289 ENSP00000383146
ENST00000400288 ENSP00000383145
ENST00000432498 ENSP00000402679
ENST00000443011 ENSP00000401199
ENST00000411518 ENSP00000391339
ENST00000444859 ENSP00000411793
ENST00000450787 ENSP00000389364
ENST00000452250 ENSP00000405541
ENST00000417682 ENSP00000398871
ENST00000425671 ENSP00000416931
ENST00000465646
ENST00000465437
ENST00000524296 ENSP00000430488
ENST00000486708
ENST00000476010
ENST00000484806
ENST00000478887
ENST00000467357
ENST00000488883
ENST00000466991
ENST00000491973
ENST00000463436
ENST00000495107
ENST00000474741
ENST00000476577
ENST00000464333
ENST00000540643 ENSP00000443025
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019902 phosphatase binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005814 centriole
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Loss of Nlp from mitotic centrosomes pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Cell Cycle pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Mitotic G2-G2/M phases pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt A8K8P3
TrEMBL X6RJF9
UniProt Splice Variant
Entrez Gene 9814
UniGene Hs.62209 Hs.679749
RefSeq NM_014775 XM_005261872 NM_001258326 NM_001258327 NM_001007467 NM_001258325 XM_005261873 XM_006724389 XM_006724390 XM_006724388 XM_005261869 XM_005261868
HUGO HGNC:29064
OMIM 612765
CCDS CCDS43005 CCDS58804 CCDS43004 CCDS58803
HPRD 11550
IMGT
EMBL AB011114 AK292408 AK293987 AK303362 AL096701 AL096768 AL109802 BC021576 BC110814 BC129926 BC129945
GenPept AAH21576 AAI10815 AAI29927 AAI29946 BAA25468 BAF85097 BAH11642 BAH13949 CAH70755 CAI12881 CAI23034 CAM13202 CAM14700 CAM14701 CAM28334 CAX14857 CAX14858 CAX15240 CAX15241
RNA Seq Atlas 9814