Version 5.4
Homo sapiens Gene: XPO4
Summary
InnateDB Gene IDBG-13860.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol XPO4
Gene Name exportin 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132953
Encoded Proteins
IDBP-13862
exportin 4
IDBP-227818
exportin 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary XPO4 belongs to a large family of karyopherins (see MIM 602738) that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments (Lipowsky et al., 2000 [PubMed 10944119]).[supplied by OMIM, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:20777329-20903048
Strand Reverse strand
Band q12.11
Transcripts
ENST00000255305 ENSP00000255305
ENST00000400602 ENSP00000383444
ENST00000490513
ENST00000465018
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0046827 positive regulation of protein export from nucleus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021952
View Gene Order
ENSBTAG00000003710
Not yet available
Pathways
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.507452 Hs.592852 Hs.743487
RefSeq NM_022459 XM_005266502 XM_005266504
HUGO
OMIM
CCDS CCDS41872
HPRD 18307
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca