Version 5.4
Mus musculus Gene: Pcdhac2
Summary
InnateDB Gene IDBG-139382.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcdhac2
Gene Name protocadherin alpha 10
Synonyms A830022B16Rik; Cnr1; Cnr3; Cnr7; Cnr8; Crnr1; Crnr3; Crnr7; Crnr8; Pcdha14; R75250
Species Mus musculus
Ensembl Gene ENSMUSG00000007440
Encoded Proteins
IDBP-139384
protocadherin alpha 11
IDBP-139388
protocadherin alpha 11
IDBP-139390
protocadherin alpha 11
IDBP-139392
protocadherin alpha 11
IDBP-249134
protocadherin alpha 11
IDBP-249136
protocadherin alpha 11
IDBP-249138
protocadherin alpha 11
IDBP-249140
protocadherin alpha 11
IDBP-249142
protocadherin alpha 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000243232:
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:36930285-37187657
Strand Forward strand
Band B2
Transcripts
ENSMUST00000070797 ENSMUSP00000068828
ENSMUST00000047614 ENSMUSP00000047609
ENSMUST00000007584 ENSMUSP00000007584
ENSMUST00000047479 ENSMUSP00000039888
ENSMUST00000115662 ENSMUSP00000111326
ENSMUST00000115661 ENSMUSP00000111325
ENSMUST00000115659 ENSMUSP00000111323
ENSMUST00000115658 ENSMUSP00000111322
ENSMUST00000115657 ENSMUSP00000111321
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000243232
View Gene Order
Cross-References
SwissProt
TrEMBL Q8BRP3 Q8K488 Q91Y09
UniProt Splice Variant
Entrez Gene 353237
UniGene Mm.308500 Mm.397407 Mm.405362 Mm.409242 Mm.412343 Mm.468629
RefSeq NM_001003672 NM_001003671 NM_007766 NM_009960 NM_009961 NM_054072 NM_138661 NM_138663 NM_198117
OMIM
CCDS CCDS29168 CCDS29166 CCDS29167 CCDS37774 CCDS37775 CCDS37776 CCDS37777 CCDS37778 CCDS37779
HPRD
IMGT
MGI ID MGI:1298370 MGI:1298371 MGI:1298372 MGI:1298406 MGI:1298408 MGI:1891442 MGI:1891443 MGI:2150982 MGI:2447322 MGI:2681880
MGI Symbol Pcdha1 Pcdha10 Pcdha11 Pcdha12 Pcdha2 Pcdha4 Pcdha5 Pcdha9 Pcdhac1 Pcdhac2
EMBL AC020968 AC020972 AC020973 AF464179 AK043822 AY013769
GenPept AAK26058 AAM93578 BAC31663
RNA Seq Atlas 116731 12936 12942 12943 192161 192164 353234 353236 353237

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca