Mus musculus Gene: Mgam
Summary
InnateDB Gene IDBG-139435.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mgam
Gene Name maltase-glucoamylase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000068587
Encoded Proteins
maltase-glucoamylase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000257335:
This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59%% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:40628831-40769123
Strand Forward strand
Band B1
Transcripts
ENSMUST00000071535 ENSMUSP00000071466
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004558 alpha-glucosidase activity
GO:0016160 amylase activity
GO:0030246 carbohydrate binding
GO:0032450 maltose alpha-glucosidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Starch and sucrose metabolism pathway
Galactose metabolism pathway
Carbohydrate digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Digestion of dietary carbohydrate pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Metabolism pathway
Disease pathway
Glycogen storage diseases pathway
KEGG
Galactose metabolism pathway
Starch and sucrose metabolism pathway
Carbohydrate digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL B5THE2
UniProt Splice Variant
Entrez Gene 232714
UniGene Mm.33401
RefSeq NM_001171003
OMIM
CCDS CCDS51755
HPRD
IMGT
MGI ID MGI:1203495
MGI Symbol Mgam
EMBL AC153378 AC158685 EU937529
GenPept ACH86011
RNA Seq Atlas 232714