InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Chd1

Summary

InnateDB Gene

IDBG-140118.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Chd1

Gene Name

chromodomain helicase DNA binding protein 1

Synonyms

2010110K24Rik; 2410085M17Rik; 4930525N21Rik; AI851787; AW555109

Species

Mus musculus

Ensembl Gene

ENSMUSG00000023852

Encoded Proteins

IDBP-140120

chromodomain helicase DNA binding protein 1

IDBP-620802

chromodomain helicase DNA binding protein 1

IDBP-620803

chromodomain helicase DNA binding protein 1

IDBP-620804

chromodomain helicase DNA binding protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000153922:
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:15704967-17394898

Strand

Forward strand

Band

Transcripts

ENSMUST00000024627	ENSMUSP00000024627
ENSMUST00000173311	ENSMUSP00000134091
ENSMUST00000173159
ENSMUST00000174461	ENSMUSP00000134718
ENSMUST00000173040	ENSMUSP00000133406

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003824	catalytic activity
GO:0004386	helicase activity
GO:0004674	protein serine/threonine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0016773	phosphotransferase activity, alcohol group as acceptor
GO:0016787	hydrolase activity
GO:0035064	methylated histone binding

Biological Process

GO:0006333	chromatin assembly or disassembly
GO:0006338	chromatin remodeling
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006468	protein phosphorylation
GO:0008150	biological_process
GO:0008152	metabolic process
GO:0009103	lipopolysaccharide biosynthetic process

Cellular Component

GO:0005575	cellular_component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016020	membrane

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000153922

View Gene Order

ENSBTAG00000020860

Not yet available

Cross-References

SwissProt

P40201 Q9CQS5

TrEMBL

Q8C7Q2 Q9CRD9 Q9D5K6

UniProt Splice Variant

Entrez Gene

67045

UniGene

Mm.419504 Mm.482565 Mm.488637 Mm.8137

RefSeq

NM_007690 NM_025934 XM_006524814 XM_006524816

OMIM

CCDS

CCDS28416 CCDS28417

HPRD

IMGT

MGI ID

MGI:88393

MGI Symbol

Chd1

EMBL

AC102745 AK008385 AK008451 AK015218 AK021188 AK049232 AK049686 BC010781 BC115822 CH466630 CT033750 L10410

GenPept

AAB08486 AAH10781 AAI15823 BAB25639 BAB25676 BAB29753 BAB32322 BAC33625 BAC33872 EDL20454

RNA Seq Atlas

12648 67045