Version 5.4
Homo sapiens Gene: CHD1
Summary
InnateDB Gene IDBG-35192.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHD1
Gene Name chromodomain helicase DNA binding protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000153922
Encoded Proteins
IDBP-35194
chromodomain helicase DNA binding protein 1
IDBP-482032
chromodomain helicase DNA binding protein 1
IDBP-477555
chromodomain helicase DNA binding protein 1
IDBP-810685
chromodomain helicase DNA binding protein 1
IDBP-810679
chromodomain helicase DNA binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:98853985-98928957
Strand Reverse strand
Band q21.1
Transcripts
ENST00000284049 ENSP00000284049
ENST00000414220
ENST00000514344
ENST00000512392
ENST00000512844 ENSP00000422589
ENST00000513064
ENST00000505657 ENSP00000422225
ENST00000511067 ENSP00000479403
ENST00000508756
ENST00000511628
ENST00000505982
ENST00000614616 ENSP00000483667
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 58 [view]
Protein-Protein 57 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0035064 methylated histone binding
Biological Process
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023852
View Gene Order
ENSBTAG00000020860
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.625092 Hs.643465 Hs.718669
RefSeq NM_001270 XM_005271867
HUGO
OMIM
CCDS CCDS34204
HPRD 03668
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca