Version 5.4
Mus musculus Gene: 1110008L16Rik
Summary
InnateDB Gene IDBG-140605.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol 1110008L16Rik
Gene Name RIKEN cDNA 1110008L16 gene
Synonyms mKIAA0391; Mrpp3
Species Mus musculus
Ensembl Gene ENSMUSG00000021023
Encoded Proteins
IDBP-140607
RIKEN cDNA 1110008L16 gene
IDBP-789152
RIKEN cDNA 1110008L16 gene
IDBP-789153
RIKEN cDNA 1110008L16 gene
IDBP-789155
RIKEN cDNA 1110008L16 gene
IDBP-789158
RIKEN cDNA 1110008L16 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000258790:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:55299577-55382533
Strand Forward strand
Band C1
Transcripts
ENSMUST00000021411 ENSMUSP00000021411
ENSMUST00000184980 ENSMUSP00000139123
ENSMUST00000184249
ENSMUST00000184766 ENSMUSP00000139204
ENSMUST00000183475 ENSMUSP00000139252
ENSMUST00000183654 ENSMUSP00000138821
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008033 tRNA processing
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000258790
View Gene Order
ENSBTAG00000009682
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03050
Proteasome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_025373
OMIM
CCDS CCDS49068
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca